2-氨基-2-甲基-1-丙醇合成路线 (共 271 条)
反应条件
1: in chloroform T=80°C; P=206.859 - 517.148 Torr; 0.166667 h; microwave irradiation; 2: With thionyl chloride in chloroform T=80°C; 0.0333333 h; microwave irradiation;
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
1: in dichloromethane T=20°C; 18 h; 2: With thionyl chloride in dichloromethane Further stages.;
参考文献
Clayden, Jonathan; Stimson, Christopher C.; Keenan, Martine
Chemical Communications, 2006 , # 13 p. 1393 - 1394
反应条件
Kaolinitic clay T=165°C; 24 h;
参考文献
Jnaneshwara; Deshpande; Lalithambika; Ravindranathan; Bedekar
Tetrahedron Letters, 1998 , vol. 39, # 5-6 p. 459 - 462
反应条件
in acetonitrile RT, 2 h, then reflux, 8 h;
参考文献
Singh, Harjit; Sarin, Rakesh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 81 - 82
反应条件
in acetonitrile 8 h;
参考文献
Singh, Harjit; Sarin, Rakesh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 81 - 82
反应条件
in nitromethane 6 h; Heating;
参考文献
Booth, Brian L.; Jibodu, Kehinde O.; Proenca, M. Fernanda J. R. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1067 - 1073
反应条件
in ethanol 20 h; Ambient temperature;
参考文献
Butt,M.I. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 2328 - 2332
反应条件
Lanthanum chloride; n-butyllithium 1) toluene, 0 deg C, 15 min then 0 to 100 deg C, 2) toluene, reflux, 12 h; Yield given. Multistep reaction;
参考文献
Marchand, Anne; Maxwell, Anderson; Mootoo, Baldwin; Pelter, Andrew; Reid, Alicia
Tetrahedron, 2000 , vol. 56, # 37 p. 7331 - 7338
反应条件
in anhydrous xylene 48 h; Reflux;
参考文献
Vessecchi, Ricardo; Tomaz, Jose Carlos; Santos, Guilherme Purcote Dos; De Oliveira, Alfredo R. Marques; Lopes, Norberto Peporine; Clososki, Giuliano Cesar
Rapid Communications in Mass Spectrometry, 2012 , vol. 26, # 9 p. 1061 - 1069
反应条件
Lanthanum chloride; n-butyllithium 1) toluene, 0 deg C, 15 min then 0 to 100 deg C, 2) toluene, reflux, 12 h; Yield given. Multistep reaction;
参考文献
Zhou, Peiwen; Blubaum, Jason E.; Burns, Christopher T.; Natale, Nicholas R.
Tetrahedron Letters, 1997 , vol. 38, # 40 p. 7019 - 7020