(2-氯-3-喹啉)甲醇合成路线 （共 11 条）
反应条件
sodium tetrahydroborate in ethanol T=0 - 20°C;
参考文献
Tetrahedron, , vol. 53, # 32 p. 11049 - 11060
反应条件
lithium diisopropyl amide Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 114, # 27 p. 10971 - 10972
反应条件
1: CF3SO3H, H2O / tetrahydrofuran / 5 h / 17 - 22 °C 2: t-BuNH2BH3 / tetrahydrofuran; H2O / 10 - 15 °C View Scheme
参考文献
Synlett, , # 1 p. 59 - 60
反应条件
1: 80 - 90 °C 2: sodium tetrahydroborate; water / 0.02 h / 20 °C View Scheme
参考文献
Chemical Papers, , vol. 64, # 6 p. 812 - 817
反应条件
zinc dibromide in toluene 2 h; Reflux;
参考文献
Cao, Hai Thuong; Gree, Rene
Tetrahedron Letters, 2009 , vol. 50, # 13 p. 1493 - 1494
反应条件
1: PBr3 2: 87 percent / t-BuOK / 1,2-dimethoxy-ethane / 48 h / Heating 3: 59 percent / Pd(OAc)2, Bu4N(1+)*Br(1-), KOAc / dimethylformamide / 3 h / 90 °C View Scheme
参考文献
Zhao, Lei; Xiong, Fang-Jun; Chen, Wen-Xue; Chen, Fen-Er
Synthesis, 2011 , # 24 art. no. F87011SS, p. 4045 - 4049
反应条件
thionyl chloride in benzene T=90°C; 4 h; Inert atmosphere;
参考文献
Barl, Nadja M.; Sansiaume-Dagousset, Elodie; Monzon, Gabriel; Wagner, Andreas J.; Knochel, Paul
Organic Letters, 2014 , vol. 16, # 9 p. 2422 - 2425
反应条件
zinc dibromide in toluene 2 h; Reflux;
参考文献
Cao, Hai Thuong; Gree, Rene
Tetrahedron Letters, 2009 , vol. 50, # 13 p. 1493 - 1494
反应条件
sodium iodide in acetonitrile 36 h; Heating;
参考文献
Narasimhan, Nurani S.; Sunder, Nurani M.; Ammanamanchi, Radhakrishna; Bonde, Bhagavat D.
Journal of the American Chemical Society, 1990 , vol. 112, # 11 p. 4431 - 4435
反应条件
sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran T=25°C; 3 h; Inert atmosphere;
参考文献
Chelucci, Giorgio
Tetrahedron Letters, 2010 , vol. 51, # 12 p. 1562 - 1565
