1: N,N-dimethyl acetamide With trifluoromethylsulfonic anhydride in anhydrous dichloroethane T=-12°C; 2: 1-bromo-4-ethenylbenzene With 2,4,6-trimethyl-pyridine in anhydrous dichloroethane T=150°C; 3: With water in anhydrous dichloroethane T=80°C; 20 h;
参考文献
PFIZER INC.; ASPNES, Gary, Erik; DOW, Robert, Lee; MUNCHHOF, Michael, John
Patent: WO2010/86820 A1, 2010 ;
Location in patent: Page/Page column 43 ;
WO 2010/086820 A1