(2S)-1-氧杂螺[2.5]辛-2-基甲醇合成路线 （共 2 条）
反应条件
1: triethylamine / dichloromethane / 0.25 h / 0 °C 2: water / 10 h / 20 °C 3: copper(l) iodide / tetrahydrofuran / 8 h / -40 °C View Scheme
参考文献
Chavan, Subhash P.; Pawar, Kailash P.; Garai, Sumanta
RSC Advances, 2014 , vol. 4, # 28 p. 14468 - 14470
反应条件
<b>Multi-step reaction with 2 steps<br /> </b>1: 1.) NaH, 2.) DIBAL / 1.) benzene, 2.) toluene, room temperature, 2 h<br />2: 80 percent / Ti(OiPr)4, L-(+)-DET, (CH<sub>3</sub>)3COOH, 4 Angstroem sieves / CH<sub>2</sub>Cl<sub>2</sub> / 2 h / -25 °C<br /> <br />
参考文献
Sabol; Cregge Tetrahedron Letters, 1990 , vol. 31, # 1 p. 27 - 30
