2-乙酰基-1-甲苯磺酰基吡咯合成路线 （共 9 条）
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; water T=0°C;
参考文献
APIBIO; BIOMERIEUX
Patent: US2006/189555 A1, 2006 ;
Location in patent: Page/Page column 12-13 ;
反应条件
boron trifluoride diethyl etherate in 1,2-dichloro-ethane T=25°C; 2 h;
参考文献
Hou, Shifa; Ding, Mengxian; Gao, Lianxun
Macromolecules, 2003 , vol. 36, # 11 p. 3826 - 3832
反应条件
trifluoroacetic anhydride in dichloromethane T=20°C; 30 h;
参考文献
Song, Chuanjun; Knight, David W.; Whatton, Maria A.
Tetrahedron Letters, 2004 , vol. 45, # 52 p. 9573 - 9576
反应条件
aluminium trichloride
参考文献
Huffman, John W.; Smith, Valerie J.; Padgett, Lea W.
Tetrahedron, 2008 , vol. 64, # 9 p. 2104 - 2112
反应条件
1: 61 percent / potassium / tetrahydrofuran / 20 °C 2: 80.5 percent / BF3*OEt2 / 1,2-dichloro-ethane / 2 h / 25 °C View Scheme
参考文献
Hou, Shifa; Ding, Mengxian; Gao, Lianxun
Macromolecules, 2003 , vol. 36, # 11 p. 3826 - 3832
反应条件
ethylaluminum dichloride in 1,2-dichloro-ethane T=0°C; Friedel-Crafts reaction; 2 h;
参考文献
Huffman, John W.; Smith, Valerie J.; Padgett, Lea W.
Tetrahedron, 2008 , vol. 64, # 9 p. 2104 - 2112
反应条件
sodium hydroxide in methanol 4 h; Heating;
参考文献
Hou, Shifa; Ding, Mengxian; Gao, Lianxun
Macromolecules, 2003 , vol. 36, # 11 p. 3826 - 3832
反应条件
sodium tetrahydroborate in isopropyl alcohol T=0 - 85°C; 26 h; Inert atmosphere;
参考文献
Frederich, James H.; Harran, Patrick G.
Journal of the American Chemical Society, 2013 , vol. 135, # 10 p. 3788 - 3791
反应条件
1: 94.4 percent / aq. NaOH / methanol / 4 h / Heating
2: 45.1 percent / trifluoroacetic anhydride / benzene / 336000 h / 20 °C
View Scheme
参考文献
Hou, Shifa; Ding, Mengxian; Gao, Lianxun
Macromolecules, 2003 , vol. 36, # 11 p. 3826 - 3832
