1: With trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone in tetrahydrofuran T=20°C; 0.666667 h; Inert atmospherelarge scale reaction; 2: With sodium hydroxide in tetrahydrofuran; water pH=12;
参考文献
Alkermes, Inc.
Patent: US2011/275803 A1, 2011 ;
Location in patent: Page/Page column 60-61 ;
