2-[4-[(E)-1,2-二苯基丁-1-烯基]苯氧基]-N,N-二甲基-乙胺合成路线 （共 46 条）
反应条件
sodium hydroxide; Pd0(tris(tert-butyl)phosphine)2 in tetrahydrofuran T=60°C; Suzuki-Miyaura coupling; 24 h;
参考文献
Kamei, Toshiyuki; Itami, Kenichiro; Yoshida, Jun-Ichi
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1824 - 1835
反应条件
sodium hydroxide; Pd0(tris(tert-butyl)phosphine)2 in tetrahydrofuran T=60°C; 24 h;
参考文献
Shimizu, Masaki; Nakamaki, Chihiro; Shimono, Katsuhiro; Schelper, Michael; Kurahashi, Takuya; Hiyama, Tamejiro
Journal of the American Chemical Society, 2005 , vol. 127, # 36 p. 12506 - 12507
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water Suzuki-Miyaura cross-coupling; Heating;
参考文献
McKinley, Neola F.; O'Shea, Donal F.
Journal of Organic Chemistry, 2006 , vol. 71, # 25 p. 9552 - 9555
反应条件
1: 55 percent / Pd2(dba)3; P(t-Bu)3; aq. KOH / tetrahydrofuran / 5 h / 20 °C 2: 75 percent / Pd[P(t-Bu)3]2; aq. NaOH / tetrahydrofuran / 24 h / 60 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 36 p. 12506 - 12507
反应条件
1: 55 percent / Pd2(dba)3; P(t-Bu)3; aq. KOH / tetrahydrofuran / 5 h / 20 °C 2: 75 percent / Pd[P(t-Bu)3]2; aq. NaOH / tetrahydrofuran / 24 h / 60 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 36 p. 12506 - 12507
反应条件
1.1: 52 percent / diethyl ether; tetrahydrofuran / 16 h / 20 °C 2.1: BCl3 / CH2Cl2 / 5 h / -41 °C 2.2: 82 percent / Et3N / CH2Cl2 / 14 h / 20 °C 3.1: 95 percent / aq. NaOH / Pd[P(t-Bu)3]2 / tetrahydrofuran / 24 h / 60 °C View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 346, # 13-15 p. 1824 - 1835
反应条件
1.1: BCl3 / CH2Cl2 / 5 h / -41 °C 1.2: 82 percent / Et3N / CH2Cl2 / 14 h / 20 °C 2.1: 95 percent / aq. NaOH / Pd[P(t-Bu)3]2 / tetrahydrofuran / 24 h / 60 °C View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 346, # 13-15 p. 1824 - 1835
反应条件
sodium ethanolate in ethanol 24 h; Heating;
参考文献
Al-Hassan, Mohammed I.
Synthetic Communications, 1987 , vol. 17, # 10 p. 1247 - 1252
反应条件
1.1: tetrahydrofuran; dibutyl ether / 2 h / -10 °C 1.2: 51 percent / triisopropyl borate / tetrahydrofuran; dibutyl ether / -78 - 20 °C 2.1: sodium carbonate / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 25 p. 9552 - 9555
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; potassium phosphate; palladium diacetate in tetrahydrofuran T=60°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere; optical yield given as percent de;
参考文献
Organic Letters, , vol. 11, # 23 p. 5434 - 5437
