in tetrahydrofuran other Radiation; microwave-accelerated preparation of arylzinc bromide by Rieke zinc insertion into aryl bromide under sealed vessel conditions for 30 min; THF 180°C; HPLC or MS;

in acetonitrile T=20°C; 2 h;

1: With acetone O-(2,4,6-trimethylphenylsulfonyl)oxime in tetrahydrofuran T=20°C; Amination; 3 h; 2: With hydrogenchloride; water T=20°C; Hydrolysis; 2 h;

1.1: CuCN; acetone O-(2,4,6-trimethylphenylsulfonyl)oxime / tetrahydrofuran / 3 h / 20 °C 1.2: 51 percent / HCl; water / 2 h / 20 °C 2.1: NaOH View Scheme