3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
triphenylphosphine; Pd bipyridyl anchored nanosized mesoporous silica MCM-41 in tetrahydrofuran Kumada-Corriu reaction; 18 h; Heating;
参考文献
Tsai, Fu-Yu; Lin, Bo-Nan; Chen, Ming-Jie; Mou, Chung-Yuan; Liu, Shiuh-Tzung
Tetrahedron, 2007 , vol. 63, # 20 p. 4304 - 4309
反应条件
(S,R)-PPF-PtBu2; bis(dibenzylideneacetone)-palladium(0) in toluene T=80°C; Kumada coupling; 1.16667 h; Inert atmosphereSealed vial;
参考文献
Lindhardt, Anders T.; Gogsig, Thomas M.; Skrydstrup, Troels
Journal of Organic Chemistry, 2009 , vol. 74, # 1 p. 135 - 143
反应条件
(i), (ii) (dehydration); Multistep reaction;
参考文献
Olah,G.A. et al.
Journal of the American Chemical Society, 1969 , vol. 91, # 6 p. 1458 - 1469
反应条件
diethyl ether und Zersetzen des Reaktionsprodukts mit Eiswasser und verd.Schwefelsaeure;
参考文献
Schwank,K.
Justus Liebigs Annalen der Chemie, 1968 , vol. 716, p. 87 - 97
反应条件
in tetrahydrofuran byproducts: LiX, MgX2; addn. of Li2MnCl4 soln. in THF to ArMgBr in THF (ratio 1:1, 0°C, under Ar), stirred (0°C, 1h); not isolated;
参考文献
Kasatkin, A. N.; Romanova, T. Yu.; Tsypyshev, O. Yu.; Tolstikov, G. A.; Lomakina, S. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 11.2 p. 2410 - 2415
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , # 11 p. 2623 - 2629
反应条件
1: 32 percent / dichlorobis(triphenylphosphine)nickel(II) / tetrahydrofuran / 24 h / Ambient temperature 2: H2, conc. HCl / PtO2 / methanol / 2585.7 Torr View Scheme
参考文献
Hacksell, Uli; Arvidsson, Lars-Erik; Svensson, Uno; Nilsson, J. Lars G.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1475 - 1482
反应条件
in tetrahydrofuran T=-78 - 20°C;
参考文献
Zarantonello, Paola; Bettini, Ezio; Paio, Alfredo; Simoncelli, Chiara; Terreni, Silvia; Cardullo, Francesco
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 2059 - 2063
参考文献
Huang
Journal of the Chemical Society, 1954 , p. 2539
反应条件
1.1: 69 percent / benzene / Heating 2.1: Na / diethyl ether / Heating 2.2: 1.6 percent / acetonitrile / 20 °C View Scheme
参考文献
Qian, Ding-Quan; Liu, Bo; Shine, Henry J.; Guzman-Jimenez, Ilse Y.; Whitmire, Kenton H.
Journal of Physical Organic Chemistry, 2002 , vol. 15, # 3 p. 139 - 147
反应条件
C35H31BrN4NiP in tetrahydrofuran T=70°C; 12 h; Schlenk techniqueInert atmosphere;
参考文献
Guo, Wang-Jun; Wang, Zhong-Xia
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1054 - 1061
