2-(2-苯基乙炔基)吡啶合成路线 （共 60 条）
反应条件
palladium dichloride in chlorobenzene 10 h; Reflux; Overall yield = 81 percent;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
palladium dichloride in chlorobenzene Reflux;
参考文献
Green Chemistry, , vol. 16, # 4 p. 2132 - 2135
反应条件
palladium dichloride in chlorobenzene 10 h; Reflux; Overall yield = 81 percent;
参考文献
Green Chemistry, , vol. 16, # 4 p. 2132 - 2135
反应条件
1: 80 percent / CHCl3 / 6 h / Heating 2: 68 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene (DBU) / benzene / 12 h / Heating View Scheme
参考文献
Sashida, Haruki; Kato, Masanobu; Tsuchiya, Takashi
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 10 p. 3826 - 3832
参考文献
Scheuing; Winterhalder
Justus Liebigs Annalen der Chemie, 1929 , vol. 473, p. 135
参考文献
Scheuing; Winterhalder
Justus Liebigs Annalen der Chemie, 1929 , vol. 473, p. 135
反应条件
copper(l) iodide; 1,10-phenanthroline; caesium carbonate in N,N-dimethyl-formamide
T=130°C; 24 h; Inert atmosphere;
参考文献
Zhao, Dongbing; Gao, Chao; Su, Xiaoyu; He, Yunqing; You, Jingsong; Xue, Ying
Chemical Communications, 2010 , vol. 46, # 47 p. 9049 - 9051
反应条件
bis-triphenylphosphine-palladium(II) chloride; (+/-)-Butanamine in water
T=25°C; Sonogashira coupling; 1.5 h; Inert atmosphere;
参考文献
Chen, Horung-Jyh; Lin, Zhe-Yi; Li, Meng-Yuan; Lian, Ruei-Jheng; Xue, Qing-Wen; Chung, Jui-Lun; Chen, Shu-Chih; Chen, Yao-Jung
Tetrahedron, 2010 , vol. 66, # 39 p. 7755 - 7761
反应条件
KOC(O)Ph; triphenylphosphine; copper(l) chloride in 1,3-dimethyl-imidazolidin-2-one
T=120°C; Sila-Sonogashira-Hagihara cross-coupling reaction; 12 h; Inert atmosphere;
参考文献
Ihara, Hideki; Ueda, Akinori; Suginome, Michinori
Chemistry Letters, 2011 , vol. 40, # 9 p. 972 - 974
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine in toluene
T=60°C; Sonogashira coupling; 16 h;
参考文献
Moulton, Benjamin E.; Whitwood, Adrian C.; Duhme-Klair, Anne K.; Lynam, Jason M.; Fairlamb, Ian J. S.
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5320 - 5334
