5-(3-硝基苯基)糠醛合成路线 （共 13 条）
反应条件
triethylamine; palladium on activated charcoal in ethanol T=60°C; Suzuki cross-coupling reaction; 2 h;
参考文献
McClure; Roschangar; Hodson; Millar; Osterhout
Synthesis, 2001 , # 11 p. 1681 - 1685
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; toluene Suzuki cross-coupling; 12 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 13 p. 3857 - 3871
反应条件
1: 3-nitro-aniline With hydrogenchloride; water; sodium nitrite T=0 - 5°C; 2: furfural With ammonium cerium(IV) nitrate in water T=20°C; 7 h;
参考文献
Subrahmanya Bhat; Shivarama Holla
Heterocyclic Communications, 2003 , vol. 9, # 6 p. 625 - 628
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium carbonate in ethylene glycol dimethyl ether; ethanol; water T=50°C; Suzuki reaction; 1 h;
参考文献
Hosoya, Takamitsu; Aoyama, Hiroshi; Ikemoto, Takaaki; Kihara, Yasutaka; Hiramatsu, Toshiyuki; Endo, Makoto; Suzuki, Masaaki
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 5 p. 663 - 673
反应条件
bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether T=50°C; Stille reaction; 18 h;
参考文献
Hosoya, Takamitsu; Aoyama, Hiroshi; Ikemoto, Takaaki; Kihara, Yasutaka; Hiramatsu, Toshiyuki; Endo, Makoto; Suzuki, Masaaki
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 5 p. 663 - 673
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; toluene Suzuki coupling; 5 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2681 - 2683
反应条件
borane dimethyl sulfide complex in tetrahydrofuran T=50 - 60°C; 2.5 h; Inert atmosphere;
参考文献
ACS Medicinal Chemistry Letters, , vol. 4, # 5 p. 475 - 480
反应条件
1.1: n-BuLi / dimethylformamide; hexane / 2 h / -20 °C 1.2: B(O-iPr)3 / dimethylformamide; hexane / -20 - 20 °C 1.3: AcOH; H2O / dimethylformamide; hexane / 20 °C 2.1: 91 percent / Et3N / 10 percent Pd/C / ethanol / 2 h / 60 °C View Scheme
参考文献
Synthesis, , # 11 p. 1681 - 1685
反应条件
CuCl2*2H2O in water; dimethyl sulfoxide T=24 - 26°C; Meerwein arylation; Mechanism; Reagent/catalystSolventTemperature;
参考文献
Obushak; Lesyuk; Gorak, Yu. I.; Matiichuk
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 9 p. 1375 - 1381
反应条件
1: 3-nitro-aniline With hydrogenchloride; sodium nitrite in water 0.166667 h; Cooling with ice; 2: furan-2-carboxylic acid With copper dichloride in water; acetone
参考文献
ACS Medicinal Chemistry Letters, , vol. 4, # 5 p. 475 - 480
