131543-46-9合成路线 （共 480 条）
反应条件
1: ethane-1,2-dial With phosphorous pentoxide; water T=20°C; 0.0833333 h; 2: urea T=20°C; 0.166667 h;
参考文献
Baccolini, Graziano; Boga, Carla; Delpivo, Camilla; Micheletti, Gabriele
Tetrahedron Letters, 2011 , vol. 52, # 14 p. 1713 - 1717
反应条件
hydrogenchloride; water
参考文献
Ritter; Lover
Journal of the American Chemical Society, 1952 , vol. 74, p. 5576
反应条件
perchloric acid 48 h; Heatingother 2-amino heterocycles, other glyoxals, other alcohols;
参考文献
Journal of Organic Chemistry, , vol. 55, # 10 p. 3143 - 3147
反应条件
ammonia in methanol; water T=10°C; 22 h;
参考文献
WO2011/15657 A1, ;
Page/Page column 17 ;
反应条件
1: 1-(tert-butoxycarbonyl)-L-proline With ammonia in methanol T=20°C; 0.5 h; 2: ethane-1,2-dial T=20 - 60°C; 16 h;
参考文献
WO2012/122716 A1, ;
Page/Page column 54-55 ;
反应条件
1: N-(tert-butyloxycarbonyl)-L-prolinol With 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; potassium hydrogencarbonate; potassium bromide in dichloromethane; water T=0 - 5°C; 0.166667 h; Inert atmosphere; 2: With sodium hypochlorite in dichloromethane; water T=0 - 5°C; 1 h; Inert atmosphere; 3: ethane-1,2-dial With ammonium hydroxide in acetonitrile T=0 - 20°C; 19 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 16, # 9 p. 2310 - 2313
反应条件
hydrogenchloride in water T=-15°C; 2.5 h;
参考文献
Abel, Edward W.; Higgins, Kevin M.; Orrell, Keith G.; Sik, Vladimir; Curzon, Eirian H.; Howarth, Oliver W.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1985 , p. 2195 - 2202
反应条件
acetic acid in methanol; water
参考文献
Gallucci, Robert R.
Journal of Chemical & Engineering Data, 1982 , vol. 27, # 2 p. 217 - 219
反应条件
in ethanol; water Heating;
参考文献
Chevallier, Floris; Blin, Thomas; Nagaradja, Elisabeth; Lassagne, Frederic; Roisnel, Thierry; Halauko, Yury S.; Matulis, Vadim E.; Ivashkevich, Oleg A.; Mongin, Florence
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 25 p. 4878 - 4885
参考文献
Pickel
Justus Liebigs Annalen der Chemie, vol. 232, p. 231
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Fischer
Chemische Berichte, vol. 17, p. 575
