1.1: Pd(OPiv)2; [bis(acetoxy)iodo]benzene / toluene / 100 °C / Inert atmosphere 1.2: 20 °C 2.1: pyridine View Scheme

1: With Pd(OPiv)2; [bis(acetoxy)iodo]benzene in toluene T=100°C; Inert atmosphere; 2: With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 3: With water in tetrahydrofuran

<b>Multi-step reaction with 3 steps<br /> </b>1: 1H-imidazole / tetrahydrofuran / 20 &deg;C / Inert atmosphere<br />2: N-bromosuccinmide / dichloromethane<br />3: water; sodium hydroxide / dichloromethane; N,N-dimethyl-formamide / 20 &deg;C<br /> <br /> &nbsp;