1,4-二甲氧基-2,3,5,6-四甲基苯合成路线 （共 9 条）
反应条件
potassium hydroxide in 1,4-dioxane; water 3 h; Inert atmosphereReflux;
参考文献
European Journal of Organic Chemistry, , # 6 p. 833 - 840
反应条件
potassium hydroxide in methanol
参考文献
Journal of Organic Chemistry, , vol. 51, # 22 p. 4160 - 4169
反应条件
1: With Bu4Mn(MgBr)2 in tetrahydrofuran T=0°C; Substitution; 10 h; 2: With water Substitution;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 73, # 9 p. 2139 - 2147
反应条件
potassium hydroxide; sodium dithionite anschliessend Erwaermen mit Dimethylsulfat;
参考文献
Helvetica Chimica Acta, , vol. 33, p. 1751,1761
反应条件
anschliessendes Behandeln mit wss. HCl;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 440,442
反应条件
nitrogen(IV) oxide in dichloromethane in the dark; -78 deg C, 2 min; RT, 15 min;
参考文献
Rathore; Bosch; Kochi
Tetrahedron, 1994 , vol. 50, # 23 p. 6727 - 6758
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 3 h; Heating; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 51, # 22 p. 4160 - 4169
反应条件
1: KOtBu, BuLi / tetrahydrofuran / 0.5 h / Ambient temperature 2: tetrahydrofuran / 16 h / Ambient temperature 3: 480 mg / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 1 h / Ambient temperature View Scheme
参考文献
Hubscher; Barner
Helvetica Chimica Acta, 1990 , vol. 73, # 4 p. 1068 - 1086
反应条件
1: KOtBu, BuLi / tetrahydrofuran / 0.5 h / Ambient temperature 2: tetrahydrofuran / 16 h / Ambient temperature 3: 480 mg / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 1 h / Ambient temperature 4: 1) H2, 2) conc. HCl / 1) 10percent Pd/C / 1) MeOH, 760 Torr, 2) 50 deg C, 2h View Scheme
参考文献
Hubscher; Barner
Helvetica Chimica Acta, 1990 , vol. 73, # 4 p. 1068 - 1086
