2-三甲基硅基-1,3-二噻吩合成路线 （共 37 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=-15°C; 1 h; Title compound not separated from byproducts;
参考文献
Andarsen, Niels H.; McCrae, David A.; Grotjahn, Douglas B.; Gabhe, Satish Y.; Theodore, Louis J.; et al.
Tetrahedron, 1981 , vol. 37, # 23 p. 4069 - 4079
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=-5°C; 0.25 h; Title compound not separated from byproducts;
参考文献
Andarsen, Niels H.; McCrae, David A.; Grotjahn, Douglas B.; Gabhe, Satish Y.; Theodore, Louis J.; et al.
Tetrahedron, 1981 , vol. 37, # 23 p. 4069 - 4079
反应条件
tetrabutyl ammonium fluoride; water-d2 in tetrahydrofuran -20 degC, 12 h; 22 degC, 1h; Title compound not separated from byproducts;
参考文献
Andarsen, Niels H.; McCrae, David A.; Grotjahn, Douglas B.; Gabhe, Satish Y.; Theodore, Louis J.; et al.
Tetrahedron, 1981 , vol. 37, # 23 p. 4069 - 4079
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=22°C; 0.2 h;
参考文献
Andarsen, Niels H.; McCrae, David A.; Grotjahn, Douglas B.; Gabhe, Satish Y.; Theodore, Louis J.; et al.
Tetrahedron, 1981 , vol. 37, # 23 p. 4069 - 4079
反应条件
n-butyllithium 1.) THF, hexane, -78 deg C, 2 h; 0 deg C, 2 h, 2.) 20 deg C, 12 h; Yield given. Multistep reaction;
参考文献
Klaveness, Jo; Rise, Frode; Undheim, Kjell
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 5 p. 373 - 380
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Benati, Luisa; Calestani, Gianluca; Nanni, Daniele; Spagnolo, Piero; Volta, Marco
Tetrahedron, 1997 , vol. 53, # 27 p. 9269 - 9278
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=-15°C; 1 h; Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4069 - 4079
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-40°C; 2 h;
参考文献
Research Foundation of State University of New York
Patent: US6340768 B1, 2002 ;
Location in patent: Example 4 ;
反应条件
in tetrahydrofuran; hexane T=-70 - 0°C; 4 h;
参考文献
MERCK PATENT GMBH
Patent: WO2004/50594 A1, 2004 ;
Location in patent: Page/Page column 18 ;
反应条件
1: 2-(trimethylsilyl)-1,3-dithiane With n-butyllithium in diethyl ether; hexane T=-30°C; 2: With copper(I) bromide dimethylsulfide complex in diethyl ether; hexane T=-60°C; 1 h; 3: 1-bromopinacolone in diethyl ether; hexane T=-60 - -30°C;
参考文献
Claessen, Rolf U.; Kornilov, Andrei M.; Banger, Kulbinder K.; Ngo, Silvana C.; Higashiya, Seiichiro; Wells, Christopher C.; Dikarev, Evgeny V.; Toscano, Paul J.; Welch, John T.
Journal of Organometallic Chemistry, 2004 , vol. 689, # 1 p. 71 - 81
