1: 3-bromo-pyridine With n-butyllithium in tetrahydrofuran; hexane T=-100°C; 0.166667 h; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane T=-100 - 0°C; 2 h;
参考文献
Le Notre, Jerome; Firet, Judith J.; Sliedregt, Leo A. J. M.; Van Steen, Bart J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein
Organic Letters, 2005 , vol. 7, # 3 p. 363 - 366
1: 85 percent / PPh3; Et3N; Pd(OAc)2 / dimethylformamide / 16 h / 130 °C 2: 85 percent / tetrabutylammonium fluoride / tetrahydrofuran / 16 h / 20 °C View Scheme
参考文献
Le Notre, Jerome; Firet, Judith J.; Sliedregt, Leo A. J. M.; Van Steen, Bart J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein
Organic Letters, 2005 , vol. 7, # 3 p. 363 - 366
1: 85 percent / PPh3; Et3N; Pd(OAc)2 / dimethylformamide / 16 h / 130 °C 2: 85 percent / tetrabutylammonium fluoride / tetrahydrofuran / 16 h / 20 °C View Scheme
参考文献
Le Notre, Jerome; Firet, Judith J.; Sliedregt, Leo A. J. M.; Van Steen, Bart J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein
Organic Letters, 2005 , vol. 7, # 3 p. 363 - 366
1: 88 percent / Et3N; PPh3; CuI / PdCl2(PPh3)2 / tetrahydrofuran / 16 h / Heating
2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 16 h / 20 °C
View Scheme
参考文献
Le Notre, Jerome; Firet, Judith J.; Sliedregt, Leo A. J. M.; Van Steen, Bart J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein
Organic Letters, 2005 , vol. 7, # 3 p. 363 - 366
