2-甲基-1,3-苯并恶唑-6-羧酸合成路线 （共 7 条）
反应条件
1: With sodium hydroxide in ethanol; water T=20°C; 2 h; 2: With hydrogenchloride in ethanol; water pH=4;
参考文献
Eisai Co., Ltd.
Patent: EP1669348 A1, 2006 ;
Location in patent: Page/Page column 68 ;
反应条件
T=100°C; 0.0833333 h; Microwave irradiation;
参考文献
McElhinny Jr., Charles J.; Lewin, Anita H.; Mascarella, S. Wayne; Runyon, Scott; Brieaddy, Lawrence; Carroll, F. Ivy
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6661 - 6664
参考文献
SANWA KAGAKU KENKYUSHO CO., LTD.
Patent: EP1595866 A1, 2005 ;
Location in patent: Page/Page column 27 ;
反应条件
1: ethanol 2: methanol; sodium hydroxide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2980 - 2985
反应条件
1: palladium on carbon; hydrogen / ethanol 2: ethanol 3: methanol; sodium hydroxide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2980 - 2985
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 1980 - 1983
反应条件
thionyl chloride; N,N-dimethyl-formamide in toluene T=70°C; 3 h;
参考文献
Dow AgroSciences LLC
Patent: EP1229037 A1, 2002 ;
Location in patent: Page 15 ;
