1,2,4-三甲氧基苯合成路线 （共 122 条）
反应条件
silver(I) acetate; potassium carbonate in 1-methyl-pyrrolidin-2-one T=120°C; 16 h; Inert atmosphere;
参考文献
Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.; Fromm, Andreas
Chemical Communications, 2009 , # 46 p. 7173 - 7175
反应条件
sodium hydride in tetrahydrofuran T=20°C; 12 h;
参考文献
Kamino, Shinichiro; Ichikawa, Hayato; Wada, Shun-ichi; Horio, Yuka; Usami, Yoshihide; Yamaguchi, Takako; Koda, Toshiki; Harada, Aki; Shimanuki, Kazusa; Arimoto, Masao; Doi, Mitsunobu; Fujita, Yoshikazu
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 15 p. 4380 - 4384
反应条件
1: 1-hydroxy-3,4-dimethoxybenzene With potassium carbonate in acetone T=40 - 45°C; 1 h; Inert atmosphere; 2: methyl iodide in acetone 7 h; RefluxInert atmosphere;
参考文献
Alves, Ana P. L.; Junior, Jose Augusto B. C.; Slana, Glaucia B. A.; Cardoso, Jari N.; Wang, Qiang; Lopes, Rosangela S. C.; Lopes, Claudio C.
Synthetic Communications, 2009 , vol. 39, # 20 p. 3693 - 3709
反应条件
potassium hydroxide 1.5 h; Heating;
参考文献
Evans; Tanis; Hart
Journal of the American Chemical Society, 1981 , vol. 103, # 19 p. 5813 - 5821
反应条件
potassium hydroxide in dimethyl sulfoxide
参考文献
Syper, Ludwik; Kloc, Krystian; Mlochowski, Jacek
Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 808 - 822
反应条件
palladium diacetate; nBu4NOAc*HOAc; tri-cyclo-hexyl-phosphine in ethylene glycol dimethyl ether T=120°C; 24 h; Inert atmosphere;
参考文献
Zhou, Jun; Wu, Ge; Zhang, Min; Jie, Xiaoming; Su, Weiping
Chemistry - A European Journal, 2012 , vol. 18, # 26 p. 8032 - 8036
反应条件
1: sodium 2,4,5-trimethoxybenzoate With palladium (II) trifluoroacetate in dimethyl sulfoxide T=80°C; 0.5 h; Inert atmosphere; 2: N-acetylindole With dimethyl sulfoxide; propionic acid in 1,4-dioxane T=80°C; 15 h; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 16, # 20 p. 5876 - 5881
反应条件
oxygen; copper; sodium carbonate; Cu2Cl2 1.) CH3CN; Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 23, # 15 p. 1577 - 1580
反应条件
sodium hydroxide; dihydrogen peroxide T=50°C; Reaktion ueber mehrere Stufen;
参考文献
Journal of the Chemical Society, , p. 1681,1683
反应条件
in water T=20 - 25°C; Oxidation; pH=3.0; KineticsEquilibrium constant;
参考文献
Journal of the American Chemical Society, , vol. 122, # 10 p. 2373 - 2374
