1,2,4-三甲氧基苯合成路线 （共 122 条）
反应条件
hydrogenchloride; aluminium trichloride in dichloromethane
参考文献
Taiho Pharmaceutical Co., Ltd.
Patent: US5786355 A1, 1998 ;
反应条件
iodine
Acetylation; 18 h; Heating;
参考文献
Al-Farhan, Emile; Amofah, Rosemary; Keehn, Philip M.; Stevenson, Robert
Organic Preparations and Procedures International, 1992 , vol. 24, # 1 p. 78 - 80
参考文献
Reigrodski; Tambor
Chemische Berichte, 1910 , vol. 43, p. 1965
Full Text Show Details
Bargellini; Avrutin
Gazzetta Chimica Italiana, 1910 , vol. 40 II, p. 349
Gazzetta Chimica Italiana, 1913 , vol. 43 I, p. 165,167 Anm.
反应条件
nitrogen(IV) oxide in dichloromethane
in the dark; -78 deg C, 2 min; RT, 15 min;
参考文献
Rathore; Bosch; Kochi
Tetrahedron, 1994 , vol. 50, # 23 p. 6727 - 6758
反应条件
manganese(IV) oxide; nitric acid
vigorous shaking;
参考文献
Errazuriz, B.; Tapia, R.; Valderrama, J. A.
Tetrahedron Letters, 1985 , vol. 26, # 7 p. 819 - 822
反应条件
nitrogen(IV) oxide in dichloromethane
T=-78°C; 2 h; UV spectra; Product distribution;
参考文献
Rathore; Bosch; Kochi
Tetrahedron, 1994 , vol. 50, # 23 p. 6727 - 6758
参考文献
Schueler
Archiv der Pharmazie (Weinheim, Germany), 1907 , vol. 245, p. 267,271
反应条件
sodium in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=100°C;
参考文献
Testaferri, L.; Tiecco, M.; Tingoli, M.; Chianelli, D.; Montanucci, M.
Tetrahedron, 1982 , vol. 38, # 24 p. 3687 - 3692
反应条件
sodium in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=100°C;
参考文献
Testaferri, L.; Tiecco, M.; Tingoli, M.; Chianelli, D.; Montanucci, M.
Tetrahedron, 1982 , vol. 38, # 24 p. 3687 - 3692
反应条件
1: chloroform; chlorine / Erhitzen des erhaltenen oeligen Reaktionsprodukts unter 20 Torr auf 150grad
2: HCl
View Scheme
参考文献
Oliverio; Castelfranchi; Simonelli
Gazzetta Chimica Italiana, 1952 , vol. 82, p. 109,110 Anm. 3
