6-甲基-2-苯基嘧啶-4-酮合成路线 （共 23 条）
反应条件
1: benzonitrile With sodium methylate in methanol T=20°C; 2: acetoacetic acid methyl ester With sodium methylate in methanol T=20 - 60°C;
参考文献
Negoro, Kenji; Yonetoku, Yasuhiro; Maruyama, Tatsuya; Yoshida, Shigeru; Takeuchi, Makoto; Ohta, Mitsuaki
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 7 p. 2369 - 2375
反应条件
sodium hydroxide in dichloromethane T=20°C; 0.25 h;
参考文献
Zanatta, Nilo; Fantinel, Leonardo; Lourega, Rogerio V.; Bonacorso, Helio G.; Martins, Marcos A. P.
Synthesis, 2008 , # 3 p. 358 - 362
反应条件
sodium ethanolate in ethanol 5 h; Heating;
参考文献
Brown; Cowden; Lan; Mori
Australian Journal of Chemistry, 1984 , vol. 37, # 1 p. 155 - 163
反应条件
sodium amide in ammonia
参考文献
Hirai, Yoshiro; Egawa, Hiroyuki; Yamada, Shoko; Yamazaki, Takao
Heterocycles, 1983 , vol. 20, # 7 p. 1243 - 1246
反应条件
ammonia in ethanol; water 0.666667 h; Heating;
参考文献
Yamamoto, Yutaka; Ohnishi, Shuhei; Azuma, Yutaka
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 6 p. 1929 - 1935
反应条件
hydroxylamine hydrochloride; triethylamine in ethanol 2 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 22, # 11 p. 1232 - 1236
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 22, # 11 p. 1523 - 1527
反应条件
tetrakis(triphenylphosphine) palladium(0); copper(I) bromide dimethylsulfide complex in tetrahydrofuran Liebeskind-Srogl cross-coupling; 24 h; Inert atmosphereReflux;
参考文献
Sun, Qi; Suzenet, Franck; Guillaumet, Gerald
Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3473 - 3476
反应条件
sodium methylate in methanol 2.5 h; Heating;
参考文献
Kato, Tetsuzo; Chiba, Takuo; Sasaki, Makoto
Heterocycles, 1981 , vol. 16, # 4 p. 577 - 580
反应条件
triethylamine in benzene 6 h; Ambient temperature;
参考文献
Marsura, Alain; Luu Duc, Cuong
Synthesis, 1982 , # 7 p. 595
反应条件
potassium hydroxide; hydroxylamine hydrochloride in ethanol 5 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 22, # 11 p. 1232 - 1236
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 22, # 11 p. 1523 - 1527
