2-氨基-3-溴吡啶合成路线

参考文献

ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC; GIJSEN, Henricus, Jacobus, Maria; MACDONALD, Gregor, James; BISCHOFF, Francois, Paul; TRESADERN, Gary, John; TRABANCO-SUAREZ, Andres, Avelino; VAN BRANDT, Sven, Franciscus, Anna; BERTHELOT, Didier, Jean-Claude
Patent: WO2010/70008 A1, 2010 ;
Location in patent: Page/Page column 60 ;
WO 2010/070008 A1

13534-99-12-氨基-3-溴吡啶+

600-18-02-酮丁酸

1204475-73-93-甲基-1H-吡咯并[2,3-B]吡啶-2-羧酸

参考文献

IRONWOOD PHARMACEUTICALS INCORPORATED; LUDRIGAN, Regina; JEFFREY, John; MERMERIAN, Ara
Patent: WO2010/5528 A2, 2010 ;
Location in patent: Page/Page column 89-90 ;

13534-99-12-氨基-3-溴吡啶+

100-06-1对甲氧基苯乙酮

139962-68-82-(4-甲氧基苯基)-1H-吡咯并[2,3-b]吡啶

参考文献

Spergel, Steven H.; Okoro, Danielle R.; Pitts, William
Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5316 - 5319

13534-99-12-氨基-3-溴吡啶+

768-60-54-乙炔基苯甲醚

139962-68-82-(4-甲氧基苯基)-1H-吡咯并[2,3-b]吡啶

参考文献

Leboho, Tlabo C.; Van Vuuren, Sandy F.; Michael, Joseph P.; De Koning, Charles B.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 2 p. 307 - 315

13534-99-12-氨基-3-溴吡啶+

108-94-1环己酮

7076-11-15,6,7,8-四氢-1H-吡啶并[2,3-b]吲哚

参考文献

Spergel, Steven H.; Okoro, Danielle R.; Pitts, William
Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5316 - 5319

13534-99-12-氨基-3-溴吡啶

67346-74-13-乙炔吡啶-2-胺

参考文献

Sumitomo Chemical Company, Limited
Patent: EP2345328 A1, 2011 ;

13534-99-12-氨基-3-溴吡啶+

403-29-22-溴-4'-氟苯乙酮

947533-47-3

参考文献

Bischoff, Francois; Berthelot, Didier; De Cleyn, Michel; MacDonald, Gregor; Minne, Garrett; Oehlrich, Daniel; Pieters, Serge; Surkyn, Michel; Trabanco, Andres A.; Tresadern, Gary; Van Brandt, Sven; Velter, Ingrid; Zaja, Mirko; Borghys, Herman; Masungi, Chantal; Mercken, Marc; Gijsen, Harrie J. M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 21 p. 9089 - 9106,18

13534-99-12-氨基-3-溴吡啶+

374538-03-12-(甲氧基羰基)苯硼酸

53439-81-9苯并[c][1,8]萘啶-6(5h)-酮

参考文献

MERCK SERONO S.A.
Patent: WO2009/108670 A1, 2009 ;
Location in patent: Page/Page column 43 ;
WO 2009/108670 A1

13534-99-12-氨基-3-溴吡啶

52333-44-5

参考文献

Garnier, Ethel; Blanchard, Stephanie; Rodriguez, Ivan; Jarry, Christian; Leger, Jean-Michel; Caubere, Paul; Guillaumet, Gerald
Synthesis, 2003 , # 13 p. 2033 - 2040

13534-99-12-氨基-3-溴吡啶

52333-48-9

参考文献

Garnier, Ethel; Blanchard, Stephanie; Rodriguez, Ivan; Jarry, Christian; Leger, Jean-Michel; Caubere, Paul; Guillaumet, Gerald
Synthesis, 2003 , # 13 p. 2033 - 2040