2-氨基-4’-溴二苯甲酮合成路线 (共 9 条)
反应条件
1: With AlCl3, aluminium chloride; boron trichloride in tetrahydrofuran Cooling with iceReflux; 2: With hydrogenchloride; water in tetrahydrofuran T=0 - 80°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 73, # 21 p. 8458 - 8468
反应条件
1: potassium acetate 2: bromine; chloroform 3: chromium (VI)-oxide; acetic acid 4: aq.-ethanolic hydrochloric acid 5: aqueous sulfuric acid / 150 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1983
反应条件
1: bromine; chloroform 2: chromium (VI)-oxide; acetic acid 3: aq.-ethanolic hydrochloric acid 4: aqueous sulfuric acid / 150 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1983
反应条件
1: chromium (VI)-oxide; acetic acid 2: aq.-ethanolic hydrochloric acid 3: aqueous sulfuric acid / 150 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1983
反应条件
1: concentrated aqueous hydrochloric acid 2: potassium acetate 3: bromine; chloroform 4: chromium (VI)-oxide; acetic acid 5: aq.-ethanolic hydrochloric acid 6: aqueous sulfuric acid / 150 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1983
反应条件
1: concentrated aqueous hydrochloric acid 2: potassium acetate 3: bromine; chloroform 4: chromium (VI)-oxide; acetic acid 5: aq.-ethanolic hydrochloric acid 6: aqueous sulfuric acid / 150 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1983
反应条件
1: With silver hexafluoroantimonate; {RuCl2(1-methyl-4-(1-methylethyl)benzene)}2; copper (II) acetate monohydrate in 1,2-dichloro-ethane T=100°C; 24 h; Inert atmosphereSchlenk technique; 2: With sulfuric acid T=0 - 20°C; 2 h; Inert atmosphereSchlenk technique; 3: With sodium hydrogencarbonate Inert atmosphereSchlenk technique;
参考文献
Chemical Communications, , vol. 49, # 45 p. 5225 - 5227
反应条件
hydrogenchloride; sodium nitrite
T=10°C; anschliessendes Erhitzen;
参考文献
Koelsch
Journal of the American Chemical Society, 1944 , vol. 66, p. 1983
反应条件
1: With hydrogenchloride; sodium nitrite in water
T=0°C; 0.55 h;
2: With hydrogenchloride; tin(ll) chloride in water
T=0 - 20°C; 1.16667 h;
3: With sodium hydroxide in water
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2008/57856 A2, 2008 ;
Location in patent: Page/Page column 123 ;