1: resin-bound p-carboxyphenylboronic acid With thionyl chloride in toluene T=70°C; Substitution; 12 h; 2: butan-1-ol With pyridine in toluene T=25°C; Esterification; 24 h; 3: With Ag(NH3)NO3 in tetrahydrofuran Protodeboronation; 8 h; Heating; Further stages.;
参考文献
Pourbaix, Christelle; Carreaux, Francois; Carboni, Bertrand; Deleuze, Herve
Chemical Communications, 2000 , # 14 p. 1275 - 1276