2-溴-1-萘-1-乙酮合成路线 （共 26 条）
反应条件
1: 1.) NaH / 1.) 0 deg C, 2.) glyme, RT, overnight
2: NaOH, water / methanol / 45 h / Heating
3: 97 percent / 192 - 210 °C
View Scheme
参考文献
Morin, Frederick G.; Horton, Walter J.; Grant, David M.; Pugmire, Ronald J.
Journal of Organic Chemistry, 1985 , vol. 50, # 18 p. 3380 - 3388
反应条件
in DMF (N,N-dimethyl-formamide)
T=0 - 20°C;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2005/72732 A1, 2005 ;
Location in patent: Page/Page column 59 ;
WO 2005/072732 A1
反应条件
Behandeln des Reaktionsprodukts mit Kaliumjodid in Wasser;
参考文献
Hartwell; Kornberg
Journal of the American Chemical Society, 1946 , vol. 68, p. 1131
参考文献
Hartwell; Kornberg
Journal of the American Chemical Society, 1946 , vol. 68, p. 1131
参考文献
Kroehnke
Chemische Berichte, 1936 , vol. 69, p. 921,924
参考文献
Hartwell; Kornberg
Journal of the American Chemical Society, 1946 , vol. 68, p. 1131
