2,5-二甲基-对苯醌合成路线 （共 118 条）
反应条件
indium; sodium iodide in N,N-dimethyl-formamide
T=20°C;
参考文献
Pan, Dipanjan; Mal, Sajal K; Kar, Gandhi K; Ray, Jayanta K
Tetrahedron, 2002 , vol. 58, # 14 p. 2847 - 2852
反应条件
in N,N-dimethyl-formamide
T=-23°C; 3 h;
参考文献
Araki, Shuki; Katsumura, Nobuhito; Butsugan, Yasuo
Journal of Organometallic Chemistry, 1991 , vol. 415, # 1 p. 7 - 24
反应条件
sodium dithionite; methanesulfonic acid in diethyl ether; water
T=85°C; 3 h; Inert atmosphere;
参考文献
Reddy, M. V. Ramana; Mallireddigari, Muralidhar R.; Pallela, Venkat R.; Cosenza, Stephen C.; Billa, Vinay K.; Akula, Balaiah; Subbaiah, D. R. C. Venkata; Bharathi, E. Vijaya; Padgaonkar, Amol; Lv, Hua; Gallo, James M.; Reddy, E. Premkumar
Journal of Medicinal Chemistry, 2013 , vol. 56, # 13 p. 5562 - 5586
反应条件
1: sodium dithionite / diethyl ether; water
2: methanesulfonic acid / 3 h / 70 °C / Inert atmosphere
View Scheme
参考文献
PROMEGA CORPORATION; BENINK, Helene; CALI, James, J.; DUELLMAN, Sarah; KLAUBERT, Dieter; LEIPPE, Donna; O'BRIEN, Martha; SHULTZ, John; VIDUGIRIENE, Jolanta; ZHOU, Wenhui; SOBOL, Mary
Patent: WO2013/33515 A1, 2013 ;
反应条件
18-crown-6 ether; potassium carbonate in dichloromethane
10 h; other reagent (triethylamine in MeOH); Product distribution;
参考文献
Aldersley, Michael F.; Dean, Francis M.; Nayyir-Mazhir, Rassoul
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1753 - 1757
反应条件
sodium acetate; acetic anhydride; zinc
参考文献
Smith; Opie
Journal of Organic Chemistry, 1941 , vol. 6, p. 427,431
参考文献
Hasegawa, Kan-ichi; Ueno, Yoshio
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 2 p. 510 - 517
反应条件
hydrogenchloride in ethanol; water
18 h; Ambient temperature;
参考文献
Ueno
Pharmazie, 1984 , vol. 39, # 5 p. 355 - 356
反应条件
2: 75 percent / NaOH / methanol; H2O
3: 90 percent / TiCl4 / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Iyer; Liebeskind
Journal of the American Chemical Society, 1987 , vol. 109, # 9 p. 2759 - 2770
反应条件
titanium tetrachloride in dichloromethane
4 h;
参考文献
Aumueller, Alexander; Huenig, Siegfried
Liebigs Annalen der Chemie, 1986 , # 1 p. 142 - 164
