(4-甲基苯基)-1-哌啶基-甲酮合成路线 （共 45 条）
反应条件
1: potassium 4-methylbenzenecarbothiolate With diphenylantimony(III) bromide
2: piperidine in dichloromethane
T=20°C; 6 h;
参考文献
Kimura, Mitsutoshi; Iwata, Akiyuki; Itoh, Masahiro; Yamada, Kazuki; Kimura, Tsutomu; Sugiura, Noriyuki; Ishida, Masaru; Kato, Shinzi
Helvetica Chimica Acta, 2006 , vol. 89, # 4 p. 747 - 783
反应条件
tert.-butylhydroperoxide; potassium carbonate in tetrahydrofuran
T=80°C; 12 h; Sealed tube;
参考文献
Zhao, Qiong; Li, Hongji; Wang, Lei
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 39 p. 6772 - 6779
反应条件
in dichloromethane
T=5°C; 0.333333 h;
参考文献
Ishihara, Hideharu; Muto, Shinya; Kato, Shinzi
Synthesis, 1986 , # 1 p. 128 - 130
反应条件
1: triethylamine / diethyl ether
2: water; acetonitrile / 25 °C
View Scheme
参考文献
Lee, Jong Pal; Bae, Ae Ri; Im, Li-Ra; Um, Ik-Hwan
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 12 p. 3588 - 3592
反应条件
Al2(NMe2)6 in toluene
T=90°C; 16 h; Equilibrium constant;
参考文献
Hoerter, Justin M.; Otte, Karin M.; Gellman, Samuel H.; Cui, Qiang; Stahl, Shannon S.
Journal of the American Chemical Society, 2008 , vol. 130, # 2 p. 647 - 654
反应条件
Al2(NMe2)6 in toluene
T=90°C; 16 h; Equilibrium constantKinetics;
参考文献
Hoerter, Justin M.; Otte, Karin M.; Gellman, Samuel H.; Cui, Qiang; Stahl, Shannon S.
Journal of the American Chemical Society, 2008 , vol. 130, # 2 p. 647 - 654
反应条件
1.1: lithium chloride; magnesium / tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere
1.2: 0.5 h / 0 °C / |Inert atmosphere
1.3: 2 h / 20 °C / |Inert atmosphere
2.1: tetrahydrofuran / 1 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Dohi, Souya; Moriyama, Katsuhiko; Togo, Hideo
European Journal of Organic Chemistry, 2013 , # 34 p. 7815 - 7822
反应条件
in water; dimethyl sulfoxide; acetonitrile
T=25°C; Kinetics;
参考文献
Jeon, Seong Hoon; Kim, Hyun Soo; Han, Young Joon; Kim, Min-Young; Um, Ik-Hwan
Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 2 p. 471 - 476
反应条件
in tetrahydrofuran
T=20°C; 1 h; Inert atmosphere;
参考文献
Dohi, Souya; Moriyama, Katsuhiko; Togo, Hideo
European Journal of Organic Chemistry, 2013 , # 34 p. 7815 - 7822
反应条件
1: tetrahydrofuran / 12 h / 0 - 25 °C / Inert atmosphere
2: trifluorormethanesulfonic acid / 12 h / 50 °C / Inert atmosphere
View Scheme
参考文献
Raja, Erum K.; Nilsson Lill, Sten O.; Klumpp, Douglas A.
Chemical Communications, 2012 , vol. 48, # 65 p. 8141 - 8143
