(4-甲基苯基)-1-哌啶基-甲酮合成路线 （共 45 条）
反应条件
sodium hydroxide
T=95°C;
参考文献
Autenrieth; Thomae
Chemische Berichte, 1924 , vol. 57, p. 1003
Chemische Berichte, 1924 , vol. 57, p. 426
反应条件
1: triethylamine / diethyl ether
2: acetonitrile / 25 °C
View Scheme
参考文献
Um, Ik-Hwan; Bae, Ae Ri
Journal of Organic Chemistry, 2011 , vol. 76, # 18 p. 7510 - 7515
反应条件
hydrogenchloride in dimethyl sulfoxide; acetonitrile
T=25°C; Substitution; Kinetics;
参考文献
Um, Ik-Hwan; Min, Ji-Sook; Ahn, Jung-Ae; Hahn, Hyun-Joo
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5659 - 5663
反应条件
in ethanol
T=78°C; 12 h;
参考文献
Tani, Kazuyasu; Hanabusa, Shin-Ichi; Kato, Shinzi; Mutoh, Shin-Ya; Suzuki, Shun-Ichi; Ishida, Masaru
Journal of the Chemical Society. Dalton Transactions, 2001 , # 5 p. 518 - 527
反应条件
in ethanol
T=20°C; 3 h;
参考文献
Tani, Kazuyasu; Hanabusa, Shin-Ichi; Kato, Shinzi; Mutoh, Shin-Ya; Suzuki, Shun-Ichi; Ishida, Masaru
Journal of the Chemical Society. Dalton Transactions, 2001 , # 5 p. 518 - 527
反应条件
potassium chloride in ethanol; water
T=25°C; pH=10.52; Kinetics; Further Variations:pH-values;
参考文献
Castro, Enrique A.; Aguayo, Raul; Bessolo, Jorge; Santos, Jose G.
Journal of Organic Chemistry, 2005 , vol. 70, # 19 p. 7788 - 7791
反应条件
water in dimethyl sulfoxide
T=25°C; aminolysis; Kinetics;
参考文献
Um, Ik-Hwan; Min, Ji-Sook; Lee, Hye-Won
Canadian Journal of Chemistry, 1999 , vol. 77, # 5-6 p. 659 - 666
反应条件
in water; dimethyl sulfoxide
T=25°C; Kinetics;
参考文献
Um, Ik-Hwan; Lee, Ji-Youn; Ko, Seung-Hak; Bae, Sun-Kun
Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5800 - 5803
反应条件
in water; dimethyl sulfoxide
T=25°C; Kinetics;
参考文献
Um, Ik-Hwan; Lee, Ji-Youn; Ko, Seung-Hak; Bae, Sun-Kun
Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5800 - 5803
反应条件
in ethanol; water
T=25°C; pH=10.52; ionic strength of 0.2 mol/L; Kinetics; Further Variations:pH-values;
参考文献
Castro, Enrique A.; Aguayo, Raul; Bessolo, Jorge; Santos, Jose G.
Journal of Physical Organic Chemistry, 2006 , vol. 19, # 8-9 p. 555 - 561
