5-甲基-2-(三甲基硅烷基)吡啶合成路线 (共 2 条)
反应条件
1: 3-Methylpyridine With n-butyllithium; LiDMAE in hexane
T=0°C; Metallation; 1 h;
2: chloro-trimethyl-silane in tetrahydrofuran; hexane
T=-78°C; Substitution; 1 h; Further stages.;
参考文献
Mathieu, Julien; Gros, Philippe; Fort, Yves
Chemical Communications, 2000 , # 11 p. 951 - 952
反应条件
iodine; magnesium in tetrahydrofuran
T=70°C; 1 h;
参考文献
Effenberger, Franz; Krebs, Andreas; Willrett, Peter
Chemische Berichte, 1992 , vol. 125, # 5 p. 1131 - 1140