1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2 h; 2: With water in tetrahydrofuran; ethyl acetate

1: With 1,1,3,3-tetramethyldisiloxane; vanadium triisopropoxide oxide in toluene T=100°C; 26 h; Inert atmosphereSealed tube; 2: With tetrabutyl ammonium fluoride in tetrahydrofuran; toluene 2 h; Inert atmosphere;

1: thien-3-yl bromide With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.25 h; 2: ethylene glycol cyclic sulfate in tetrahydrofuran; hexane T=-78 - 20°C; 3: With sulfuric acid in tetrahydrofuran; hexane 4 h; Heating; Further stages.;

diethyl ether T=-70°C;

暂无反应条件数据

1: 98 percent / I2, Ph3P, imidazole / CH2Cl2 / 3 h / Ambient temperature 2: 1.) NaH / 1.) THF, 2.) THF, RT, 1 h 3: 96 percent / aq. KOH / ethanol / 7 h / Heating 4: 67 percent / bis-(2-hydroxy-ethyl) ether / 3 h View Scheme

1: 98 percent / I2, Ph3P, imidazole / CH2Cl2 / 3 h / Ambient temperature 2: 1.) NaH / 1.) THF, 2.) THF, RT, 1 h View Scheme

1: 98 percent / I2, Ph3P, imidazole / CH2Cl2 / 3 h / Ambient temperature 2: 1.) NaH / 1.) THF, 2.) THF, RT, 1 h 3: 96 percent / aq. KOH / ethanol / 7 h / Heating View Scheme

in acetonitrile T=684.8°C; Pyrolysis; Kinetics; Further Variations:Temperatures;

1.1: dichloromethane / 20 °C 1.2: 20.08 h / 14 - 30 °C 2.1: sodium hydroxide; water / dichloromethane / Cooling with ice 3.1: 2-methyl tetrahydrofuran / 22 °C 4.1: 2,2,6,6-tetramethyl-piperidine; n-butyllithium / hexane; tetrahydrofuran / -78 - -70 °C / Inert atmosphere 4.2: -20 °C / Inert atmosphere 5.1: hydrogenchloride; water / isopropyl alcohol / 6.5 h / 45 °C View Scheme