1-环己基-2-氟-1-戊酮合成路线 （共 5 条）
反应条件
ethylmagnesium bromide in diethyl ether T=-78°C; 0.0833333 h;
参考文献
Satoh, Tsuyoshi; Itoh, Norifumi; Onda, Ken-ichi; Kitoh, Yasushi; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 10 p. 2800 - 2806
反应条件
1: oxalyl chloride, dimethyl sulfoxide / CH2Cl2 / 0.25 h / -60 °C 2: 85 percent / EtMgBr / diethyl ether / 0.08 h / -78 °C View Scheme
参考文献
Satoh, Tsuyoshi; Itoh, Norifumi; Onda, Ken-ichi; Kitoh, Yasushi; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 10 p. 2800 - 2806
反应条件
1: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2.) THF, -78 deg C, 5 min 2: oxalyl chloride, dimethyl sulfoxide / CH2Cl2 / 0.25 h / -60 °C 3: 85 percent / EtMgBr / diethyl ether / 0.08 h / -78 °C View Scheme
参考文献
Satoh, Tsuyoshi; Itoh, Norifumi; Onda, Ken-ichi; Kitoh, Yasushi; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 10 p. 2800 - 2806
反应条件
1: 1.) LDA / 1.) -78 deg C, THF 2: 89 percent / Swern Oxidation 3: 1.) EtMgBr, 2.) H2O / 1.) ether, -78 deg C View Scheme
参考文献
Satoh, Tsuyoshi; Onda, Ken-ichi; Itoh, Norifumi; Yamakawa, Koji
Tetrahedron Letters, 1991 , vol. 32, # 40 p. 5599 - 5600
反应条件
1: 89 percent / Swern Oxidation 2: 1.) EtMgBr, 2.) H2O / 1.) ether, -78 deg C View Scheme
参考文献
Satoh, Tsuyoshi; Onda, Ken-ichi; Itoh, Norifumi; Yamakawa, Koji
Tetrahedron Letters, 1991 , vol. 32, # 40 p. 5599 - 5600
