反应条件
1: caesium carbonate / tetrakis(triphenylphosphine) palladium(0) / ethylene glycol dimethyl ether; water; industrial methylated spirit / 0.3 h / 120 °C / Inert atmosphere; Microwave irradiation 2: ammonium formate / palladium 10 on activated carbon / water; industrial methylated spirit / 0.5 h / Reflux 3: hydrogenchloride / 1,4-dioxane / 1 h View Scheme
参考文献
THE UNIVERSITY OF EDINBURGH; WEBSTER, Scott, Peter; SECKL, Jonathan, Robert; WALKER, Brian, Robert; WARD, Peter; PALLIN, Thomas, David; DYKE, Hazel, Joan; PERRIOR, Trevor, Robert
Patent: WO2011/33255 A1, 2011 ;
WO 2011/033255 A1