1: piperazine; piperazine Dihydrochloride in water 0.0833333 h; 2: 1-acetyl-1H-imidazole With sodium chloride in water 0.5 h; 3: With sodium hydroxide in water chemoselective reaction;
in water T=15 - 45°C; ionic strength 0.2 M and 0.6 M (KCl), ΔH(excit.), ΔS(excit.), structure-reactivity correlations in the aminolysis; Rate constantThermodynamic dataMechanism;
参考文献
Journal of Organic Chemistry, , vol. 54, # 9 p. 2153 - 2159