4-氯-2-三甲基甲硅烷基吡啶合成路线 （共 19 条）
反应条件
1: 4-Chloro-pyridine With n-butyllithium in hexane T=-78°C; 1 h; 2: chloro-trimethyl-silane With 1,2,2-trichloro-1,1,2-trichloro-ethane in tetrahydrofuran; hexane T=-78 - 20°C; 1 h;
参考文献
European Journal of Organic Chemistry, , # 3 p. 603 - 606
反应条件
iodine; magnesium in tetrahydrofuran T=70°C; 1 h;
参考文献
Chemische Berichte, , vol. 125, # 5 p. 1131 - 1140
反应条件
tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; silver(l) oxide in N,N-dimethyl-formamide T=90°C; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773
反应条件
tetrakis(triphenylphosphine) palladium(0); silver fluoride; silver(l) oxide in N,N-dimethyl-formamide T=90°C; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773
反应条件
potassium fluoride; tetrakis(triphenylphosphine) palladium(0); silver(l) oxide in N,N-dimethyl-formamide T=90°C; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773
反应条件
tetrabutyl ammonium fluoride; silver(l) oxide in N,N-dimethyl-formamide T=20°C; 12 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; triphenylphosphine in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 12 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 51, # 27 p. 3558 - 3560
反应条件
tetrakis(triphenylphosphine) palladium(0); silver fluoride; silver(l) oxide in N,N-dimethyl-formamide T=90°C; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773
反应条件
copper(l) iodide; tetrabutyl ammonium fluoride; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; Hiyama cross-coupling; 12 h;
参考文献
Pierrat, Philippe; Gros, Philippe; Fort, Yves
Organic Letters, 2005 , vol. 7, # 4 p. 697 - 700
反应条件
tetrabutyl ammonium fluoride; silver(l) oxide in N,N-dimethyl-formamide T=20°C; 12 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773
