N-乙酰基-(2R)-莰烷-10,2-磺内酰胺合成路线 （共 10 条）
反应条件
in acetonitrile 4 h; Heating;
参考文献
Jung, Jae-Chul; Kache, Rajashaker; Vines, Kimberly K.; Zheng, Yan-Song; Bijoy, Panicker; Valluri, Muralikrishna; Avery, Mitchell A.
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9269 - 9284
反应条件
sodium hydride in tetrahydrofuran T=20°C; 0.75 h;
参考文献
Altmann, Karl-Heinz; Bold, Guido; Caravatti, Giorgio; Denni, Donatienne; Floersheimer, Andreas; Schmidt, Alfred; Rihs, Grety; Wartmann, Markus
Helvetica Chimica Acta, 2002 , vol. 85, # 11 p. 4086 - 4110
反应条件
1: (1S,2R,4R)-2,10-camphorsultam With n-butyllithium in tetrahydrofuran; hexane T=-78°C; Metallation; 0.5 h; 2: acetic pivalic mixed anhydride in tetrahydrofuran; hexane T=-78°C; Acetylation; Further stages.;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 20 p. 3406 - 3416
反应条件
in acetonitrile T=40°C; 48 h;
参考文献
Ward, Robert S.; Pelter, Andrew; Goubet, Dominique; Pritchard, Martyn C.
Tetrahedron: Asymmetry, 1995 , vol. 6, # 2 p. 469 - 498
反应条件
1: 99 percent / thionyl chloride / DMF / 3 h / 20 °C 2: 100 percent / ammonium hydroxide / dioxane / 6 h / 20 - 95 °C 3: 66 percent / sodium borohydride / methanol; H2O / 1 h / 5 °C 4: 95 percent / sodium hydride / toluene / 16 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 26 p. 9269 - 9284
反应条件
(NH4)2S2O8; trifluorormethanesulfonic acid T=70°C; 3 h;
参考文献
Tetrahedron Asymmetry, , vol. 15, # 24 p. 3869 - 3878
参考文献
Wu, Wen-Xue; McPhail, Andrew T.; Porter, Ned A.
Journal of Organic Chemistry, 1994 , vol. 59, # 6 p. 1302 - 1308
反应条件
1: 100 percent / ammonium hydroxide / dioxane / 6 h / 20 - 95 °C 2: 66 percent / sodium borohydride / methanol; H2O / 1 h / 5 °C 3: 95 percent / sodium hydride / toluene / 16 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 26 p. 9269 - 9284
反应条件
1: 66 percent / sodium borohydride / methanol; H2O / 1 h / 5 °C 2: 95 percent / sodium hydride / toluene / 16 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 26 p. 9269 - 9284
反应条件
1.1: TiCl4; iPr2EtN / CH2Cl2 / 0.5 h / -78 °C
1.2: 83 percent / CH2Cl2 / 6 h / -78 °C
2.1: pyridine / CH2Cl2 / 20 °C
3.1: DBU / CH2Cl2
View Scheme
参考文献
Harding, John R.; Hughes, Rachael A.; Kelly, Nicholas M.; Sutherland, Andrew; Willis, Christine L.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3406 - 3416
