2-甲基-4,5-二苯唑合成路线 （共 46 条）
反应条件
sulfuric acid; formamide 1.) 110 deg C, 1 h, 2.) 140-150 deg C, 2 h;
参考文献
Pei, Weiwei; Li, Shaohui; Nie, Xiaoping; Li, Yiwei; Pei, Jian; Chen, Bingzi; Wu, Jie; Ye, Xiulin
Synthesis, 1998 , # 9 p. 1298 - 1304
反应条件
1: With pyridine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=10 - 20°C; 2.5 h; 2: With ammonium chloride; acetic acid 2 h; Reflux;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; LOPEZ, Omar D.; ST. LAURENT, Denis R.; GOODRICH, Jason; ROMINE, Jeffrey Lee; SERRANO-WU, Michael; YANG, Fukang; KAKARLA, Ramesh; YANG, Xuejie; QIU, Yuping; SNYDER, Lawrence B.
Patent: WO2011/82077 A1, 2011 ;
Location in patent: Page/Page column 215-216 ;
反应条件
trifluorormethanesulfonic acid; benzenetellurinyl trifluoromethanesulfonate 2 h; Heating;
参考文献
Fukumoto, Takahiro; Aso, Yoshio; Otsubo, Tetsuo; Ogura, Fumio
Journal of the Chemical Society, Chemical Communications, 1992 , # 15 p. 1070 - 1072
反应条件
trimethylsilyl trifluoromethanesulfonate in 1,2-dichloro-ethane T=23 - 80°C; Ritter reaction; Inert atmosphere;
参考文献
Lai, Ping-Shan; Taylor, Mark S.
Synthesis, 2010 , # 9 art. no. M06109SS, p. 1449 - 1452
反应条件
in acetonitrile T=60 - 80°C; 2 h;
参考文献
Kotani, Eiichi; Kobayashi, Shigeki; Adachi, Mayumi; Tsujioka, Toshiyuki; Nakamura, Kouji; Tobinaga, Seisho
Chemical & Pharmaceutical Bulletin, 1989 , vol. 37, # 3 p. 606 - 609
反应条件
[bis(acetoxy)iodo]benzene; boron trifluoride diethyl etherate in 1,2-dichloro-ethane 2 h; Reflux;
参考文献
Zheng, Yunhui; Li, Xuming; Ren, Chengfeng; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10353 - 10361
反应条件
sulfuric acid T=30 - 40°C;
参考文献
Bal'on, Ya. G.; Smirnov, V. A.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 9.2 p. 1712 - 1715
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 9 p. 1983 - 1987
反应条件
1: α-phenylacetophenone With PhI(ODNs)OH 0.0111111 h; microwave irradiation; 2: acetamide 0.0333333 h; microwave irradiation;
参考文献
Lee, Jong Chan; Choi, Hyun Jung; Lee, Yong Chan
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 123 - 125
反应条件
1: α-phenylacetophenone With (hydroxy(tosyloxy)iodo)benzene 0.025 h; microwave irradiation; 2: acetonitrile microwave irradiation; Further stages.;
参考文献
Lee, Jong Chan; Seo, Jang-Woo; Baek, Jong Wook
Synthetic Communications, 2007 , vol. 37, # 13 p. 2159 - 2162
反应条件
diphenyl diselenide; water; bis-[(trifluoroacetoxy)iodo]benzene T=40°C; 14 h;
参考文献
European Journal of Organic Chemistry, , # 2 p. 399 - 404
