2-[[(1,1-二甲基乙氧基)羰基]氨基]-2-(二甲氧基膦)乙酸乙酯合成路线 （共 2 条）
反应条件
in tetrahydrofuran Arbuzov reaction; 2 h; Heating;
参考文献
Vartak, Ashish P.; Skoblenick, Kevin; Thomas, Nancy; Mishra, Ram K.; Johnson, Rodney L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 26 p. 6725 - 6729
反应条件
1: NaH / tetrahydrofuran / 1 h / 0 - 20 °C
2: H2 / Pd/C / methanol / 3 h / 2068.59 Torr
3: ethyl acetate / 24 h / Heating
View Scheme
参考文献
Rosauer, Keith G.; Ogawa, Anthony K.; Willoughby, Chris A.; Ellsworth, Kenneth P.; Geissler, Wayne M.; Myers, Robert W.; Deng, Qiaolin; Chapman, Kevin T.; Harris, Georgianna; Moller, David E.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 24 p. 4385 - 4388
