sodium acetate T=90 - 100°C; 4.75 h;

bis-triphenylphosphine-palladium(II) chloride T=80°C; 2 h; Yields of byproduct given;

pyrrolidine; Pd(OAc)2*PPh3 4 h; Heating;

1: 87 percent / (PPh3)2PdCl2 / 2 h / 80 °C / var. 2-bromoallyl acetates, other secondary and tertiary cyclic amines 2: pyrrolidine, triphenylphospine / palladium acetate View Scheme