(S)-(-)-1-苯基乙醇合成路线 (共 393 条)
反应条件
in dichloromethane T=23°C; 0.166667 h; Inert atmosphere; enantioselective reaction;
参考文献
Kelly, Brendan D.; Lambert, Tristan H.
Journal of the American Chemical Society, 2009 , vol. 131, # 39 p. 13930 - 13931
反应条件
di-tert-butylazodicarboxylate; triphenylphosphine in tetrahydrofuran T=-40°C; Mitsunobu reaction; Inert atmosphere;
参考文献
Laha, Joydev K.; Cuny, Gregory D.
Journal of Organic Chemistry, 2011 , vol. 76, # 20 p. 8477 - 8482
反应条件
1: SOCl2 2: sodium ethylate; ethanol / anschliessendes Behandeln mit Kalilauge und Erhitzen des Reaktionsprodukts View Scheme
参考文献
Levene; Marker
Journal of Biological Chemistry, 1932 , vol. 97, p. 379,381
反应条件
1: (S)-alpha-methylbenzyl alcohol With tert.-butyl lithium in diethyl ether; pentane T=-78 - 20°C; 4 h; 2: methyl iodide in diethyl ether; pentane T=-78 - 20°C; 19 h;
参考文献
Granander, Johan; Sott, Richard; Hilmersson, Goeran
Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 439 - 447
反应条件
n-butyllithium in hexane; toluene T=0°C; 16 h;
参考文献
Sokeirik, Yasser Samir; Sato, Kazuyuki; Omote, Masaaki; Ando, Akira; Kumadaki, Itsumaro
Tetrahedron Letters, 2006 , vol. 47, # 16 p. 2821 - 2824
反应条件
sodium hydrogencarbonate; [{(η5-C5Me5)IrCl}2(μ-Cl)2] in toluene T=110°C; 17 h;
参考文献
Fujita, Ken-ichi; Enoki, Youichiro; Yamaguchi, Ryohei
Tetrahedron, 2008 , vol. 64, # 8 p. 1943 - 1954
反应条件
boron trifluoride diethyl etherate e.e.= 2percent (S); Product distributionMechanism;
参考文献
Smonou, Ioulia; Orfanopoulos, Michael
Tetrahedron Letters, 1988 , vol. 29, # 45 p. 5793 - 5796
反应条件
zinc(II) iodide in 1,2-dichloro-ethane
参考文献
Gauthier, Jacques Yves; Bourdon, France; Young, Robert Norman
Tetrahedron Letters, 1986 , vol. 27, # 1 p. 15 - 18
反应条件
zinc dibromide in dichloromethane T=20°C; Arbuzov reaction; Inert atmosphere;
参考文献
Rajeshwaran, Ganesan Gobi; Nandakumar, Meganathan; Sureshbabu, Radhakrishnan; Mohanakrishnan, Arasambattu K
Organic Letters, 2011 , vol. 13, # 6 p. 1270 - 1273
参考文献
Freudenberg; Todd; Seidler
Justus Liebigs Annalen der Chemie, 1933 , vol. 501, p. 208
Full Text Show Details
Levene; Stevens
Journal of Biological Chemistry, 1930 , vol. 89, p. 471,474