2′-羟基-5′-溴苯乙酮合成路线 （共 81 条）
反应条件
aluminium trichloride in nitrobenzene 4 h; 1.) to 120 deg C, 1 h, 2.) 150 deg C, 3 h;
参考文献
Journal of Chemical Research, Miniprint, , # 11 p. 2713 - 2739
反应条件
boron trifluoride T=120°C; unter Druck;
参考文献
Chemische Berichte, , vol. 87, p. 194,201
反应条件
1: Heating; 2: With aluminium trichloride T=125 - 1300°C;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 40, # 5 p. 635 - 640
反应条件
N-bromosuccinmide T=80°C; 10 h; regioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 77, # 13 p. 5823 - 5828
反应条件
aluminium trichloride
反应条件
bromine; acetic acid
参考文献
Polish Journal of Chemistry, , vol. 57, # 1/3 p. 49 - 56
参考文献
Journal of the American Chemical Society, , vol. 55, p. 4657,4660
反应条件
1: 96 percent / pyridine / 70 °C 2: 84 percent / t-BuOK / tetrahydrofuran / 20 °C 3: 82 percent / CuBr2 / dimethylformamide / 0.17 h / 130 °C View Scheme
参考文献
Marder, Mariel; Zinczuk, Juan; Colombo, Maria I.; Wasowski, Cristina; Viola, Haydee; Wolfman, Claudia; Medina, Jorge H.; Ruveda, Edmundo A.; Paladini, Alejandro C.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 15 p. 2003 - 2008
反应条件
in hexane; ethyl acetate; N,N-dimethyl-formamide
参考文献
Mackman, Richard Laurence
Patent: US2002/45650 A1, 2002 ;
反应条件
1: N,N-dimethyl-formamide With bis(trichloromethyl) carbonate in 1,2-dichloro-ethane T=0 - 20°C; 2: 5'-bromo-2'-hydroxyacetophenone in 1,2-dichloro-ethane T=0 - 20°C; 4.5 h; Further stages.;
参考文献
Su; Li; Zhao
Organic Preparations and Procedures International, 2007 , vol. 39, # 5 p. 495 - 502
