2-氯烟酸乙酯合成路线

参考文献

De, B.; Winn, M.; Zydowsky, T. M.; Kerkman, D. J.; DeBernardis, J. F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 20 p. 3714 - 3717

110-89-4哌啶+

1452-94-42-氯烟酸乙酯

192817-83-7

参考文献

Leost, Francoise; Chantegrel, Bernard; Deshayes, Christian
Tetrahedron, 1997 , vol. 53, # 22 p. 7557 - 7576

115377-94-12-BOC-氨基苯基硼酸+

1452-94-42-氯烟酸乙酯

23985-95-7

参考文献

Ferraris, Dana; Ko, Yao-Sen; Pahutski, Thomas; Ficco, Rica Pargas; Serdyuk, Larisa; Alemu, Christina; Bradford, Chadwick; Chiou, Tiffany; Hoover, Randall; Huang, Shirley; Lautar, Susan; Liang, Shi; Lin, Qian; Lu, May X.-C.; Mooney, Maria; Morgan, Lisa; Qian, Yongzhen; Tran, Scott; Williams, Lawrence R.; Wu, Qi Yi; Zhang, Jie; Zou, Yinong; Kalish, Vincent
Journal of Medicinal Chemistry, 2003 , vol. 46, # 14 p. 3138 - 3151

1452-94-42-氯烟酸乙酯+

146140-95-62-(2,2,2-三甲基乙酰氨基)苯硼酸

参考文献

Audoux, Jerome; Achelle, Sylvain; Turck, Alain; Marsais, Francis; Ple, Nelly
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1497 - 1503

1452-94-42-氯烟酸乙酯

27038-48-8呋喃并[2,3-b]吡啶-3(2H)-酮

参考文献

Morita, Hiroyuki; Shiotani,Shunsaku
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 1465 - 1469

77152-08-0+

1452-94-42-氯烟酸乙酯

208517-35-52-三氟甲基烟酸乙酯

参考文献

Lishchynskyi, Anton; Novikov, Maxim A.; Martin, Eddy; Escudero-Adan, Eduardo C.; Novak, Petr; Grushin, Vladimir V.
Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11126 - 11146

557-21-1氰化锌+

1452-94-42-氯烟酸乙酯

75358-90-62-氰基烟酸乙酯

参考文献

Merck Sharp and Dohme Limited
Patent: WO2004/46133 A1, 2004 ;
Location in patent: Page 31 ;
WO 2004/046133 A1

参考文献

RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281396 A1, 2013 ;
Location in patent: Paragraph 0305-0306 ;

124-41-4甲醇钠+

1452-94-42-氯烟酸乙酯

67367-26-42-甲氧基烟酸甲酯

参考文献

RESVERLOGIX CORP.; JOHANSSON, Jan, O.; HANSEN, Henrik, C.; CHIACCHIA, Fabrizio, S.; WONG, Norman, C.W.
Patent: WO2007/16525 A2, 2007 ;
Location in patent: Page/Page column 48-49; 56-57; 69-71; 75-76; 99-101 ;
WO 2007/016525 A2

6340-91-6丙基肼草酸盐 (1:1)+

1452-94-42-氯烟酸乙酯

1016230-29-71-丙基-1H-吡唑并[3,4-b]吡啶-3(2H)-酮

参考文献

Cappelli, Andrea; Nannicini, Chiara; Gallelli, Andrea; Giuliani, Germano; Valenti, Salvatore; Mohr, Galla Pericot; Anzini, Maurizio; Mennuni, Laura; Ferrari, Flora; Caselli, Gianfranco; Giordani, Antonio; Peris, Walter; Makovec, Francesco; Giorgi, Gianluca; Vomero, Salvatore
Journal of Medicinal Chemistry, 2008 , vol. 51, # 7 p. 2137 - 2146