4-氧代-4H-色烯-2-羧酸乙酯合成路线 （共 18 条）
反应条件
sodium ethanolate in ethanol 1 h; Heating;
参考文献
MERCK PATENT GMBH
Patent: WO2006/94601 A1, 2006 ;
Location in patent: Page/Page column 43 ;
反应条件
sulfuric acid; sodium ethanolate in ethanol; hexane; water; toluene
参考文献
Briggs, Barbara; Kanter, James; Mullins, John J.G.; Ruhter, Gerd; Udodong, Uko; Zmijewski Jr., Milton; Verral II, Daniel
Patent: US2004/53992 A1, 2004 ;
反应条件
hydrogenchloride; sodium ethanolate in ethanol; water
参考文献
Laboratorios Menarini S.A.
Patent: US5990142 A1, 1999 ;
反应条件
DPAT in toluene T=80°C; 4 h;
参考文献
Sakamoto, Masami; Yagishita, Fumitoshi; Kanehiro, Masayuki; Kasashima, Yoshio; Mino, Takashi; Fujita, Tsutomu
Organic Letters, 2010 , vol. 12, # 20 p. 4435 - 4437
反应条件
toluene-4-sulfonic acid in benzene 4 h; Reflux;
参考文献
Sarkar, Debayan; Venkateswaran, Ramanathapuram V.
Tetrahedron, 2011 , vol. 67, # 25 p. 4559 - 4568
反应条件
1: 66 percent / Et3N / CH2Cl2 / 0.5 h 2: 79 percent / formic acid; Et3N; 1,3-bis(diphenylphosphanyl)propane / palladium(II) acetate / dimethylformamide / 1.5 h View Scheme
参考文献
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 60, # 7 p. 792 - 796
反应条件
hydrogenchloride in ethanol 0.5 h; Heating;
参考文献
Bevan, Peter S.; Ellis, Gwynn P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1705 - 1709
反应条件
1: 1.) sodium ethoxide, 2.) sulphuric acid / 1.) ethanol, reflux, 2.) 0 deg C 2: 31 percent / hydrochloric acid / ethanol / 0.5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 8 p. 1705 - 1709
反应条件
1: sodium hydride / tetrahydrofuran / 18 h / 0 - 20 °C / Inert atmosphere 2: toluene-4-sulfonic acid / benzene / 4 h / Reflux View Scheme
参考文献
Tetrahedron, , vol. 67, # 25 p. 4559 - 4568
参考文献
Journal of the Chemical Society, , vol. 79, p. 474
