N-甲基四氯邻苯二甲酰亚胺合成路线 （共 8 条）
反应条件
sulfolane T=25 - 110°C; 2.5 h; Cooling with acetone-dry ice;
参考文献
Fertel, Lawrence B.
Organic Process Research and Development, 1998 , vol. 2, # 2 p. 111 - 115
反应条件
3,4,5,6-Tetrachlorophthalic anhydride T=160°C; 120 h;
参考文献
Eaton, Jefferson T.; Rounds, William D.; Urbanowicz, John H.; Gribble, Gordon W.
Tetrahedron Letters, 1988 , vol. 29, # 50 p. 6553 - 6556
反应条件
1: 3,4,5,6-tetrachlorophthalimide With potassium hydroxide in ethanol Gabriel reaction; 2: methyl iodide in N,N-dimethyl-formamide T=20°C;
参考文献
Sou, Sonei; Takahashi, Hiroyasu; Yamasaki, Ryu; Kagechika, Hiroyuki; Endo, Yasuyuki; Hashimoto, Yuichi
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 6 p. 791 - 793
参考文献
Journal of the American Chemical Society, , vol. 56, p. 1410
反应条件
in acetonitrile T=30°C; KineticsThermodynamic data;
参考文献
Journal of the Chemical Society, Perkin Transactions 2, , # 8 p. 1449 - 1454
反应条件
sulfolane; potassium fluoride
参考文献
Fertel, Lawrence B.
Organic Process Research and Development, 1998 , vol. 2, # 2 p. 111 - 115
反应条件
potassium fluoride; sodium chloride in sulfolane; ethyl acetate
参考文献
SDS Biotech K.K.
Patent: US4769493 A1, 1988 ;
反应条件
1.1: potassium fluoride; sulfolane 2.1: sodium hydroxide; zinc / water / 1.5 h / 60 °C 2.2: 1 h / 80 °C 3.1: dimethyl sulfoxide / 125 °C View Scheme
参考文献
Fertel, Lawrence B.
Organic Process Research and Development, 1998 , vol. 2, # 2 p. 111 - 115
