1: (i) CrO3, AcOH, (ii) hydrazinocarbonylmethyl-trimethyl-ammonium chloride, (iii) KOH, MeOH 2: KOAc View Scheme

1: 84 percent / zirconium tetrachloride / CH2Cl2 / 48 h / 20 °C 2: 91.4 percent / K2CO3 / dimethylformamide / 66 h / 60 °C 3: 82.4 percent / meta-chloroperbenzoic acid; disodium phosphate / CH2Cl2 / 20 °C 4: 12.56 g / NaOH / methanol; H2O / 2 h / 60 °C 5: 92.7 percent / lithium hydroxide monohydrate / tetrahydrofuran / 3 h / Heating 6: 84.4 percent / H2 / Pd/C / ethanol / 16 h / 1965.16 Torr View Scheme

methanol; zinc

T=20°C; Hydrolysis;

T=100°C; Hydrolysis;

1: 80 percent / oxone, aq. NaHCO3, TBAHS / CH2Cl2 / 3.5 h / 15 - 20 °C 2: 95 percent / aq. H2SO4 / CH2Cl2 / -30 °C 3: 65 percent / KOH / methanol / 4 h / 40 °C View Scheme

lipase from Candida cylindracea; octanol in various solvent(s) T=37°C; 144 h;

(i) CrO3, AcOH, (ii) hydrazinocarbonylmethyl-trimethyl-ammonium chloride, (iii) KOH, MeOH; Multistep reaction;

chromium(VI) oxide; acetic acid in ethyl acetate T=20°C; 28 h;

(i) CrO3, aq. H2SO4, acetone, (ii) /BRN= 385737/, NaOAc; Multistep reaction;