6-吡啶-3-基-1H-吲哚合成路线 (共 3 条)
反应条件
potassium phosphate; tris(dibenzylideneacetone)dipalladium (0); tri-cyclo-hexyl-phosphine in 1,4-dioxane; water T=100°C; 18 h;
参考文献
Kudo, Noriaki; Perseghini, Mauro; Fu, Gregory C.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 8 p. 1282 - 1284
反应条件
palladium diacetate; sodium carbonate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in ethanol T=85°C; Suzuki-Miyaura coupling; 16 h; Inert atmosphere;
参考文献
Molander, Gary A.; Canturk, Belgin; Kennedy, Lauren E.
Journal of Organic Chemistry, 2009 , vol. 74, # 3 p. 973 - 980
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate 1.) DME, RT, 20 min, 2.) DME, reflux, 20 h; Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 13 p. 2011 - 2032