5-雄甾-3-烯-17-酮合成路线 (共 25 条)
反应条件
(i) KOH, MeOH, (ii) CrO3, acetone; Multistep reaction;
参考文献
Pascual; Wolff
Journal of medicinal chemistry, 1971 , vol. 14, # 2 p. 164 - 167
反应条件
acetic acid; zinc 0.5 h;
参考文献
Qian, Mingxing; Krishnan, Kathiresan; Kudova, Eva; Li, Ping; Manion, Brad D.; Taylor, Amanda; Elias, George; Akk, Gustav; Evers, Alex S.; Zorumski, Charles F.; Mennerick, Steven; Covey, Douglas F.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 1 p. 171 - 190
参考文献
Amiranashvili, L. Sh.; Sladkov, V. I.; Lindeman, S. V.; Aleksanyan, M. S.; Struchkov, Yu. T.; Suvorov, N. N.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 5.2 p. 906 - 911
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 5 p. 1052 - 1058
参考文献
McKenna et al.
Journal of the Chemical Society, 1959 , p. 2502,2507
反应条件
1: 96 percent / aq. H2O2; HCO2H / 1 h / 20 °C 2: dimethyl sulfoxide; (CF3CO)2O; Et3N / 3.25 h / -60 °C 3: NaOMe / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 20 p. 6379 - 6385