2-哌啶-1-基-5-(三氟甲基)苯胺合成路线 （共 4 条）
反应条件
1: With hydrogenchloride; tin(ll) chloride in methanol T=0 - 20°C; 17.5 h; 2: With water; sodium hydrogencarbonate in methanol Product distribution / selectivity;
参考文献
HAGIWARA, Masatoshi
Patent: EP1712242 A1, 2006 ;
Location in patent: Page/Page column 18; 30 ;
反应条件
1: sodium bicarbonate / tetrahydrofuran / 14 h / 70 °C 2: H2 / Pd/C / methanol / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 4 p. 627 - 640
反应条件
1: sodium bicarbonate / tetrahydrofuran / 14 h / 70 °C 2: H2 / Pd/C / methanol / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 4 p. 627 - 640
反应条件
triethylamine in dichloromethane T=0°C; 0.5 h; Product distribution / selectivity;
参考文献
HAGIWARA, Masatoshi
Patent: EP1712242 A1, 2006 ;
Location in patent: Page/Page column 18; 31 ;
