2-甲基-2,3-二氢-1H-环戊并[a]萘-1-酮合成路线 （共 11 条）
反应条件
1: With phosphorus pentachloride in toluene T=20°C; 1 h; 2: With tin(IV) chloride in toluene T=20°C; 13 h;
参考文献
Fujita, Takuma; Kuwahara, Shunsuke; Harada, Nobuyuki
European Journal of Organic Chemistry, 2005 , # 21 p. 4533 - 4543
反应条件
aluminium trichloride in dichloromethane Ambient temperature;
参考文献
Dietrich, Ulf; Hackmann, Martijn; Rieger, Bernhard; Klinga, Martti; Leskelae, Markku
Journal of the American Chemical Society, 1999 , vol. 121, # 18 p. 4348 - 4355
反应条件
aluminium trichloride in toluene Friedel-Crafts acylation;
参考文献
Vicario, Javier; Walko, Martin; Meetsma, Auke; Feringa, Ben L.
Journal of the American Chemical Society, 2006 , vol. 128, # 15 p. 5127 - 5135
反应条件
1.1: LDA / tetrahydrofuran / 1 h / -60 °C 1.2: 48 percent / tetrahydrofuran / -60 - 20 °C 2.1: 87 percent / aq. KOH / ethanol / Heating 3.1: 98 percent / SOCl2; DMF / CH2Cl2 / 1 h / Heating 4.1: AlCl3 / toluene View Scheme
参考文献
Ter Wiel, Matthijs K. J.; Van Delden, Richard A.; Meetsma, Auke; Feringa, Ben L.
Journal of the American Chemical Society, 2003 , vol. 125, # 49 p. 15076 - 15086
反应条件
1: 87 percent / aq. KOH / ethanol / Heating 2: 98 percent / SOCl2; DMF / CH2Cl2 / 1 h / Heating 3: AlCl3 / toluene View Scheme
参考文献
Ter Wiel, Matthijs K. J.; Van Delden, Richard A.; Meetsma, Auke; Feringa, Ben L.
Journal of the American Chemical Society, 2003 , vol. 125, # 49 p. 15076 - 15086
反应条件
1.1: 94 percent / H2 / Pd/C / ethanol / 14 h / 20 °C 2.1: PCl5 / toluene / 1 h / 20 °C 2.2: 98 percent / SnCl4 / toluene / 13 h / 20 °C View Scheme
参考文献
Fujita, Takuma; Kuwahara, Shunsuke; Harada, Nobuyuki
European Journal of Organic Chemistry, 2005 , # 21 p. 4533 - 4543
反应条件
1.1: 83 percent / propionic anhydride / 15 h / 180 °C 2.1: 94 percent / H2 / Pd/C / ethanol / 14 h / 20 °C 3.1: PCl5 / toluene / 1 h / 20 °C 3.2: 98 percent / SnCl4 / toluene / 13 h / 20 °C View Scheme
参考文献
Fujita, Takuma; Kuwahara, Shunsuke; Harada, Nobuyuki
European Journal of Organic Chemistry, 2005 , # 21 p. 4533 - 4543
参考文献
Cook et al.
Journal of the Chemical Society, 1935 , p. 1319,1322
反应条件
1: LiAlH4 2: p-ToS-OH / toluene View Scheme
参考文献
Woudenberg, Richard Herman
Patent: US2002/77507 A1, 2002 ;
反应条件
lithium aluminium tetrahydride
参考文献
Dietrich, Ulf; Hackmann, Martijn; Rieger, Bernhard; Klinga, Martti; Leskelae, Markku
Journal of the American Chemical Society, 1999 , vol. 121, # 18 p. 4348 - 4355
