反应条件
1: 1.) NaH / 1.) THF, RT, 1 h, 2.) THF, from -78 deg C to RT, 14 h 2: 73 percent / phosphoric acid, BF3*Et2O / CH2Cl2 / 1.) -78 deg C, 2 h, 2.) 0 deg C, 24 h 3: 65 percent / H2O / 70 h / 25 °C / bakers' yeast (Red Star) 4: 86 percent / pyridine / 16 h / 25 °C 5: p-toluenesulfonic acid monohydrate / benzene / 1.5 h / Heating 6: diethyl ether 7: 66 percent / CaCO3, CH3I / acetone; H2O / 7 h / 65 °C 8: 1.) n-BuLi, 2.) HMPA / 1.) THF, hexane, -78 deg C, 15 min, 2a.) THF, hexane, -78 deg C, 40 min, 2b.) -20 deg C, 30 min 9: 48 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 5 h / 25 °C 10: 68 percent / K2CO3 / methanol; H2O / 12 h / Ambient temperature View Scheme
参考文献
Han, Chao-Qi; DiTullio, Dennis; Wang, Yi-Fong; Sih, Charles J.
Journal of Organic Chemistry, 1986 , vol. 51, # 8 p. 1253 - 1258
