3-苯基-2-丙炔-1-醇合成路线 （共 165 条）
反应条件
titanium tetrachloride; triethylamine in dichloromethane T=0°C; 1 h;
参考文献
Synlett, , # 9 p. 1421 - 1422
反应条件
oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite in dichloromethane; acetic acid T=20°C; 2 h;
参考文献
Wang, Lianyue; Li, Jun; Yang, Hua; Lv, Ying; Gao, Shuang
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 790 - 794
反应条件
oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite in dichloromethane; acetic acid T=20°C; 10 h;
参考文献
Wang, Lianyue; Li, Jun; Yang, Hua; Lv, Ying; Gao, Shuang
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 790 - 794
反应条件
oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite in dichloromethane; acetic acid T=20°C; 3 h;
参考文献
Wang, Lianyue; Li, Jun; Yang, Hua; Lv, Ying; Gao, Shuang
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 790 - 794
反应条件
oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite in dichloromethane; acetic acid T=20°C; 10 h;
参考文献
Wang, Lianyue; Li, Jun; Yang, Hua; Lv, Ying; Gao, Shuang
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 790 - 794
反应条件
1: 3-phenyl-2-propyn-1-ol (phenyl propargyl alcohol) With lithium hydride in tetrahydrofuran T=0°C; alcoholate formation; 1 h; 2: CH3Li*CeCl3 in tetrahydrofuran T=-78 - -20°C; Addition; 24 h;
参考文献
Bartoli, Giuseppe; Bellucci, M. Cristina; Bosco, Marcella; Dalpozzo, Renato; De Nino, Antonio; Sambri, Letizia; Tagarelli, Antonio
European Journal of Organic Chemistry, 2000 , # 1 p. 99 - 104
反应条件
N,N,N',N,-tetramethylethylenediamine in diethyl ether
参考文献
Olsson,L.-I.; Claesson,A.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1976 , vol. 30, p. 521 - 526
参考文献
Duboudin,J.G.; Jousseaume,B.
Journal of Organometallic Chemistry, 1979 , vol. 168, p. 1 - 11
反应条件
1: 100 percent / Br2 / CH2Cl2 / 0 °C 2: triphenylphosphonium dibromide / CH2Cl2 / 2 h / 20 °C 3: 88 percent / toluene / 36 h / 20 °C 4: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, -70 deg C, 15 min, 2.) THF, from -70 deg C to -25 deg C, 30 min 5: benzyltrimethylammonium methoxide / methanol / 1.5 h / -30 - 0 °C View Scheme
参考文献
Ziegler, Carl B.; Harris, Sonja M.; Baldwin, J. E.
Journal of Organic Chemistry, 1987 , vol. 52, # 3 p. 443 - 446
反应条件
1.1: CCl4; PPh3
2.1: n-BuLi / diethyl ether; hexane / -78 - -15 °C
2.2: 70 percent / diethyl ether; hexane / -78 - 20 °C
View Scheme
参考文献
Pereira, Alban R.; Cabezas, Jorge A.
Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2594 - 2597
