(2-氨基-5-氯苯基)环丙基甲酮合成路线 （共 5 条）
反应条件
1: in tetrahydrofuran T=0 - 80°C; 2: With hydrogenchloride in tetrahydrofuran; water T=0 - 20°C;
参考文献
Banyu Pharmaceutical Co., Ltd.
Patent: EP2210880 A1, 2010 ;
Location in patent: Page/Page column 32 ;
反应条件
gallium(III) chloride; boron trichloride in chlorobenzene T=100°C; 20 h; Yields of byproduct given;
参考文献
Houpis, Ioannis N.; Molina, Audrey; Douglas, Alan W.; Xavier, Lyndon; Lynch, Joseph; et al.
Tetrahedron Letters, 1994 , vol. 35, # 37 p. 6811 - 6814
反应条件
gallium(III) chloride; boron trichloride 1.) CH2Cl2, 1,1,2,2-tetrachloroethane, 0 deg C, 2.) 1,1,2,2-tetrachloroethane, 100 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Douglas; Abramson; Houpis; Karady; Molina; Xavier; Yasuda
Tetrahedron Letters, 1994 , vol. 35, # 37 p. 6807 - 6810
反应条件
acetic acid in water Yield given. Yields of byproduct given;
参考文献
Houpis, Ioannis N.; Molina, Audrey; Douglas, Alan W.; Xavier, Lyndon; Lynch, Joseph; et al.
Tetrahedron Letters, 1994 , vol. 35, # 37 p. 6811 - 6814
反应条件
potassium cyanate in water Yield given. Yields of byproduct given;
参考文献
Houpis, Ioannis N.; Molina, Audrey; Douglas, Alan W.; Xavier, Lyndon; Lynch, Joseph; et al.
Tetrahedron Letters, 1994 , vol. 35, # 37 p. 6811 - 6814
